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Factors associated with global longitudinal strain decline in hypertensive patients with normal left ventricular ejection fraction

Auteurs : Nabila Soufi Taleb Bendiab, Abderrahim Meziane-Tani, Souhila Ouabdesselam, Nadera Methia, Samia Latreche, Latefa Henaoui, Jean-Jacques Monsuez, Salim Benkhedda

Date de publication : 2017/9/1

Revue : European journal of preventive cardiology

Volume : 24

Numéro : 14

Pages : 1463-1472

Éditeur : Oxford University Press

Description

Background

Early detection of risk factors for left ventricular (LV) dysfunction may be useful in patients with high blood pressure (HBP).

Methods

Patient from an outpatient HBP clinic underwent a two-dimensional Doppler-coupled echocardiography with determination of LV global longitudinal strain (GLS) by speckle-tracking.

Results

Among 200 patients (mean age 61.7 ± 9.7 years), 155 were overweight, 93 had diabetes, 83 had dyslipidemia, and 109 had uncontrolled HBP. LV hypertrophy (LVH) was found in 136 patients (68%), including concentric (n = 106) and eccentric (n = 30) LVH. Diastolic dysfunction patterns were observed in 178 patients (89%), and increased filling pressures were observed in 37 patients (18.5%). GLS ranged from –25% to –11.6% (mean –16.9 ± 3.2%). Low GLS values (>–17%) were found in 91 patients (45.5%), 68 with …